drugset / Trial / NCT00776373

Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies

NCT00776373

Phase 1/2 Terminated 4 enrolled Abramson Cancer Center at Penn Medicine
NaSingle-groupOpen-labelTreatment

Summary

Assess the safety, tolerability and efficacy of rapamycin in combination with HiVAC in relapsed and refractory patients with aggressive lymphoid malignancies.

Timeline

Start
2007-01
Primary completion
2008-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Sirolimus Small molecule 3 mg Oral
Subject Sirolimus Small molecule 4 mg Oral
Background Cytarabine Small molecule 2000 mg/m2 Intravenous
Background Etoposide Small molecule 500 mg/m2 Intravenous