drugset / Trial / NCT00777855
Drug Interaction Study of Rifampin and Warfarin in Healthy Volunteers.
RandomizedCrossoverOpen-labelBasic science
Summary
The purpose of this study is to determine the importance of uptake drug transporters in the drug disposition of warfarin. We predict that the elimination of warfarin will be decreased when co-dosed with an inhibitor of uptake drug transporters.
Timeline
- Start
- 2008-11
- Primary completion
- 2009-03
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rifampicin | Small molecule | 600 mg | Intravenous |
| Subject | Warfarin | Small molecule | 7.5 mg | Oral |
Indications
No indication recorded.