Intraoperative Glucose Control in Liver Transplant

Phase 4 Completed 100 enrolled University of Michigan

RandomizedParallel-groupOpen-labelSupportive care

Summary

The goal of the proposed study is to evaluate the effectiveness of intraoperative, strict glycemic control to improve survival and infection rates following liver transplantation in a randomized, prospective trial.Primary objective: To determine if strict intraoperative blood glucose control, when compared to standard intraoperative glycemic control, improves 1-year recipient survival and decreases surgical complications, including infections, following liver transplantation.

Timeline

Start: 2008-07
Primary completion: 2009-09
Completion: 2009-09

Publications

Kumar SS, Pelletier SJ, Shanks A, Thompson A, Sonnenday CJ, Picton P. Intraoperative glycemic control in patients undergoing Orthotopic liver transplant: a single center prospective randomized study. BMC Anesthesiol. 2020 Jan 4;20(1):3. doi: 10.1186/s12871-019-0918-0.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Insulin	Protein / enzyme biologic	—	—

Indications

No indication recorded.