drugset / Trial / NCT00782548
Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults
RandomizedCrossoverDouble-blindBasic science
Summary
The primary objective of this study was to compare the single-dose relative bioavailability of Alpharma Branded Products Division (Kadian®) and Ligand® Pharmaceuticals Inc. (AVINZA®) 30 mg morphine sulfate sustained-release capsules in healthy adult volunteers under fed conditions. The secondary objective of this study was to evaluate the adverse events associated with each of these 2 different morphine sulfate modified-release commercial formulations
Timeline
- Start
- 2004-05
- Primary completion
- 2004-06
- Completion
- 2004-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Morphine | Other / unclassified | 30 mg | — |
Indications
No indication recorded.