drugset / Trial / NCT00783744
Insulin Glargine Combination Therapies in Type II Diabetics
RandomizedParallel-groupOpen-labelTreatment
Summary
To compare efficacy of combination therapy of insulin glargine plus glimepiride and metformin versus 2 injections insulin monotherapy with premixed insulin NPH 30/70 bid in terms of change of HbA1c (baseline to endpoint) to show non-inferiority of insulin glargine plus glimepiride and metformin.
Timeline
- Start
- 2001-12
- Primary completion
- 2003-08
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Glimepiride | Small molecule | 3 mg | — |
| Subject | Glimepiride | Small molecule | 4 mg | — |
| Subject | Metformin | Small molecule | 850 mg | — |
| Subject | insulin glargine | Protein / enzyme biologic | — | — |
| Comparator | premixed insulin NPH 30/70 | Protein / enzyme biologic | — | — |