drugset

drugset / Trial / NCT00784316

Intravenous Metoprolol Versus Intravenous Amiodarone in the Prevention of Atrial Fibrillation After Cardiac Surgery

NCT00784316 ↗

Phase 4 Completed 316 enrolled Kuopio University Hospital Tampere University Hospital · collab Vaasa Central Hospital, Vaasa, Finland · collab

RandomizedParallel-groupOpen-labelPrevention

Summary

The aim of the study is to test the efficiency of intravenous administration of metoprolol versus intravenous administration of amiodarone in the prevention of atrial fibrillation after cardiac surgery.

Timeline

Start: 2007-08
Primary completion: 2009-07
Completion: 2009-07

Publications

Halonen J, Loponen P, Jarvinen O, Karjalainen J, Parviainen I, Halonen P, Magga J, Turpeinen A, Hippelainen M, Hartikainen J, Hakala T. Metoprolol versus amiodarone in the prevention of atrial fibrillation after cardiac surgery: a randomized trial. Ann Intern Med. 2010 Dec 7;153(11):703-9. doi: 10.7326/0003-4819-153-11-201012070-00003.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Amiodarone	Small molecule	15 mg/kg	Intravenous
Comparator	Metoprolol	Other / unclassified	1 mg	Intravenous
Comparator	Metoprolol	Other / unclassified	3 mg	Intravenous

Indications