drugset / Trial / NCT00785980
Drug - Drug Interaction Study of Quinine Sulfate and Ciprofloxacin
Non-randomizedSingle-groupOpen-labelBasic science
Summary
Ciprofloxacin is moderate inhibitor of cytochrome P450 1A2 (CYP1A2), one of the enzymes responsible for the metabolism of quinine. This study will evaluate the effect of ciprofloxacin-related inhibition of CYP1A2 on the pharmacokinetics of quinine sulfate.
Timeline
- Start
- 2008-09
- Primary completion
- 2008-10
- Completion
- 2008-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ciprofloxacin | Small molecule | 500 mg | Oral |
| Subject | Quinine | Small molecule | 648 mg | Oral |
Indications
No indication recorded.