Drugs / Ciprofloxacin
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Ciprofloxacin

Small molecule targets CYP1A2 via inhibition

Developed for
urinary tract infection · infectious disease · bronchiectasis · acute otitis externa · bacterial infectious disease · chronic obstructive pulmonary disease · dental pulp necrosis · anthrax infection
+101 more · cystic fibrosis · neutropenia · periapical periodontitis · appendicitis · cirrhosis of liver · gonorrhea · otitis media with effusion · ulcerative colitis · amyotrophic lateral sclerosis · cholera · chronic endometritis · colorectal cancer · Crohn disease · Crohn's colitis · dental pulp disorder · infectious disease with sepsis · malignant pancreatic neoplasm · otitis media · pancreatic ductal adenocarcinoma · pneumonia · prostate cancer · pulpitis · acute apical periodontitis · acute myeloid leukemia · anal fistula · asthma · bacteriuria · bladder transitional cell carcinoma · breast cancer · bubonic plague · castration-resistant prostate carcinoma · chlamydia trachomatis infectious disease · cholangitis · chronic bronchitis · chronic lymphocytic leukemia/small lymphocytic lymphoma · chronic prostatitis · chronic rhinosinusitis · critical illness polyneuropathy · cutaneous leishmaniasis · dental abscess · diarrheal disease · discharging ear · diverticulitis of colon · drug allergy · epilepsy · exanthem · gram-negative bacterial infections · infectious peritonitis · infective endocarditis · intestinal perforation · liver abscess (disease) · lung disorder · Mycobacterium avium complex disease · nephrolithiasis · nosocomial infection · osteomyelitis · pancreas disorder · periodontal disorder · peritonitis · plague · pneumonic plague · prostatitis · Pseudomonas infection · pyelonephritis · sexually transmitted disease · suppurative periapical periodontitis · tooth resorption · toxic dermatosis · ulcer of lower limbs · urolithiasis · abscess · acute diarrhea · acute endophthalmitis · acute leukemia · acute pyelonephritis · alcoholic hepatitis · Alzheimer disease · autoinflammatory syndrome · bacterial urinary tract infection · benign lymphoepithelial lesion of salivary gland · benign prostatic hyperplasia · cat-scratch disease · chronic periodontitis · corneal ulcer · cystitis · disease related to hematopoietic stem cell transplant · endometritis · keratitis · meningococcal meningitis · otitis externa · perianal Crohn disease · periodontitis · polyomavirus infectious disease · prosthesis-related infectious disease · Pseudomonas aeruginosa infectious disease · respiratory tract infectious disorder · rhinoscleroma · shigellosis · small intestinal bacterial overgrowth · staphylococcus aureus infection · typhoid fever
Investigated by
Bayer · Novartis · Otonomy, Inc. · Cairo University · National Institute of Allergy and Infectious Diseases (NIAID) · ZonMw: The Netherlands Organisation for Health Research and Development
+206 more · Aradigm Corporation · National Cancer Institute (NCI) · National University Hospital, Singapore · Academic Medical Center - University of Amsterdam · Ain Shams University · Al-Mustansiriyah University · Assistance Publique - Hôpitaux de Paris · Centre de recherche du Centre hospitalier universitaire de Sherbrooke · Department of Health and Human Services · Dr. Reddy's Laboratories Limited · Emergent BioSolutions · Genesis Athens Clinic · Grifols Therapeutics LLC · International Centre for Diarrhoeal Disease Research, Bangladesh · King Abdulaziz University · Korea University · Monash University · Mylan Pharmaceuticals Inc · National Institute for Health Research, United Kingdom · NeuroSense Therapeutics Ltd. · Singapore General Hospital · Tan Tock Seng Hospital · The University of Texas Health Science Center at San Antonio · University Hospital, Basel, Switzerland · University of Aarhus · University of Florida · University of Maryland, Baltimore · Vertex Pharmaceuticals Incorporated · Al-Mustafa University College · Altamash Institute of Dental Medicine · American Association of Endodontists · American Association of Obstetricians and Gynecologists Foundation (AAOGF) · American Cancer Society, Inc. · American University of Beirut Medical Center · Amgen · Andalusian Public Foundation for Health Research in Seville · Assaf Harofeh MC · Beni-Suef University · Biomedical Advanced Research and Development Authority · Boston Medical Center · British Thoracic Society · Bronovo Hospital · CHU de Quebec-Universite Laval · Canadian Critical Care Trials Group · Center for Supporting Hematology-Oncology Trials · Centers for Disease Control and Prevention · Changi General Hospital · Chulalongkorn University · Clinical Urology and Epidemiology Working Group · Consorzio per Valutazioni Biologiche e Farmacologiche · Crohn's and Colitis Foundation · Cystic Fibrosis Foundation · Danish Cancer Society · Diaconessenhuis Leiden · Dow University of Health Sciences · Dr Cipto Mangunkusumo General Hospital · Dr. D. Y. Patil Dental College & Hospital · Eastern Cooperative Oncology Group · Ege University · Elusys Therapeutics · European Organisation for Research and Treatment of Cancer - EORTC · Exela Pharma Sciences, LLC. · Faiz ur rahman · Farmoquimica S.A. · Florencia Vargas-Vorackova · Food and Drug Administration (FDA) · Foreign, Commonwealth and Development Office and Wellcome (216273.Z.19.Z) · Fundacion Clinic per a la Recerca Biomédica · GE Healthcare · GERCOR - Multidisciplinary Oncology Cooperative Group · Gary Morrow · GlaxoSmithKline · Gold Coast Hospital and Health Service · Groene Hart Ziekenhuis · all 212 on the full record

Regulatory milestones approvals, filings & regulatory actions · 17 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) OTIPRIO 2018-03-02 fda.gov
Label expansions (9) US (FDA) CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER 1996-10-10 – 2015-02-02 fda.gov
Label expansions (5) US (FDA) CIPRO 1994-07-21 – 1997-06-03 fda.gov
Label expansion US (FDA) CILOXAN 1994-10-27 fda.gov
Approved US (FDA) CIPRO 1987-10-22 fda.gov

Trials 161 · started per year

today
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198719881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT00881907 Mar 2010 → Mar 2014 dental pulp necrosis The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 0 NCT00881491 Apr 2009 → Jan 2015 dental pulp necrosis The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 129 trials
Phase 1 NCT06925490 Jun 2025 → Sep 2026 expected pulpitis Cairo University Not yet recruiting No outcome recorded
Phase 1 NCT06478940 Aug 2024 → Aug 2025 dental pulp disorder Cairo University Unknown No outcome recorded
Phase 1 NCT05724628 Oct → Nov 2023 appendicitis University of Texas Southwestern Medical Center Withdrawn No outcome recorded
Phase 1 NCT05843708 Apr → Jul 2023 Servier Bio-Innovation LLC Completed No outcome recorded
Phase 1 NCT04090684 Dec 2019 → Sep 2021 amyotrophic lateral sclerosis NeuroSense Therapeutics Ltd. Completed No outcome recorded
Phase 1 NCT04523987 Feb 2019 → Feb 2027 expected pancreatic ductal adenocarcinoma National University Hospital, Singapore Active not recruiting No outcome recorded
Phase 1 NCT01976065 Sep 2014 → Sep 2018 dental pulp necrosis Kenneth Hargreaves Completed No outcome recorded
Phase 1 NCT02118909 May → Jun 2014 Helsinn Healthcare SA Completed No outcome recorded
Phase 1 NCT02015507 Jan → Feb 2014 cystic fibrosis Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 1 NCT01952444 Oct 2013 → Apr 2014 inhalational anthrax Elusys Therapeutics Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06126731 Nov 2023 → Jun 2026 overdue castration-resistant prostate carcinoma Institute of Cancer Research, United Kingdom Recruiting No outcome recorded
Phase 1/2 NCT02773732 Dec 2016 → Sep 2021 acute myeloid leukemia University of Florida Terminated No outcome recorded
Phase 1/2 NCT01108601 Apr 2008 → Apr 2011 hearing loss disorder McGill University Health Centre/Research Institute of the McGill University Health Centre Unknown No outcome recorded
Phase 228 trials
Phase 2 NCT07028424 Jul 2025 → Jul 2029 expected pancreatic ductal adenocarcinoma GERCOR - Multidisciplinary Oncology Cooperative Group Not yet recruiting No outcome recorded
Phase 2 NCT06728072 Mar 2025 → Jul 2035 expected colorectal cancer Virginia Commonwealth University Recruiting No outcome recorded
Phase 2 NCT06798402 Feb → Nov 2025 overdue cutaneous leishmaniasis Al-Mustafa University College Recruiting No outcome recorded
Phase 2 NCT07264842 Jun 2024 → Apr 2026 overdue dental pulp necrosis Dow University of Health Sciences Recruiting No outcome recorded
Phase 2 NCT06342830 Jun 2024 → Sep 2025 periapical periodontitis Ain Shams University Completed No outcome recorded
Phase 2 NCT05462496 Mar 2023 → Aug 2027 expected malignant pancreatic neoplasm Icahn School of Medicine at Mount Sinai Recruiting No outcome recorded
Phase 2 NCT05205993 Jan 2021 → Jan 2024 chronic endometritis Genesis Athens Clinic Unknown No outcome recorded
Phase 2 NCT04165850 Nov 2019 → Jan 2021 amyotrophic lateral sclerosis NeuroSense Therapeutics Ltd. Completed No outcome recorded
Phase 2 NCT04067011 Aug 2019 → Mar 2020 anthrax infection Emergent BioSolutions Completed No outcome recorded
Phase 2 NCT05287425 Aug 2019 → Aug 2023 Medical University of Vienna Completed No outcome recorded
Phase 2/35 trials
Phase 2/3 NCT07202052 May 2025 → Mar 2027 expected leukemia, non-Hodgkin lymphoma, plasma cell myeloma Monash University Recruiting No outcome recorded
Phase 2/3 NCT05678621 Nov 2022 → Apr 2027 expected dysgammaglobulinemia, hematopoietic and lymphoid cell neoplasm Monash University Recruiting No outcome recorded
Phase 2/3 NCT04879030 Jan → Aug 2020 chronic obstructive pulmonary disease Haiphong University of Medicine and Pharmacy Completed No outcome recorded
Phase 2/3 NCT04319575 Dec 2018 → Apr 2020 suppurative periapical periodontitis Dr. D. Y. Patil Dental College & Hospital Unknown No outcome recorded
Phase 2/3 NCT07113587 Apr 2014 → Jul 2017 infectious peritonitis Karl Landsteiner Insitute for Nephrology and Haemato-Oncology Completed No outcome recorded
Phase 330 trials
Phase 3 NCT07686055 Jul 2026 → Feb 2027 expected urinary tract infection Megan Bradley Not yet recruiting No outcome recorded
Phase 3 NCT05079802 Dec 2021 → Dec 2023 tooth resorption Ain Shams University Unknown No outcome recorded
Phase 3 NCT04636957 Nov 2020 → Dec 2021 acute otitis externa Lee's Pharmaceutical Limited Unknown No outcome recorded
Phase 3 NCT04110340 Feb 2020 → Apr 2024 bubonic plague, pneumonic plague University of Oxford Completed No outcome recorded
Phase 3 NCT03303677 Apr → Nov 2018 chronic rhinosinusitis University of Florida Withdrawn No outcome recorded
Phase 3 NCT04547764 Jun 2017 → Dec 2018 dental pulp disorder King Abdulaziz University Completed No outcome recorded
Phase 3 NCT02389036 May 2017 → Apr 2023 critical illness polyneuropathy, infectious disease with sepsis The George Institute Completed No outcome recorded
Phase 3 NCT02795949 Oct 2016 → Jan 2020 bacterial infectious disease Andalusian Public Foundation for Health Research in Seville Completed No outcome recorded
Phase 3 NCT02801370 Jun → Nov 2016 acute otitis externa Otonomy, Inc. Completed No outcome recorded
Phase 3 NCT02600559 Oct 2015 → Jul 2016 otitis media Otonomy, Inc. Completed No outcome recorded
Phase 435 trials
Phase 4 NCT07704359 Aug 2026 → Feb 2029 expected anal fistula University of Illinois at Chicago Not yet recruiting No outcome recorded
Phase 4 NCT06709196 Jan 2025 → Jan 2027 expected urinary bladder cancer Rigshospitalet, Denmark Recruiting No outcome recorded
Phase 4 NCT05398679 Aug 2022 → Dec 2026 expected infective endocarditis Fundacion Clinic per a la Recerca Biomédica Recruiting No outcome recorded
Phase 4 NCT05600023 Aug → Oct 2022 pulpitis Altamash Institute of Dental Medicine Completed No outcome recorded
Phase 4 NCT05199324 Jun 2022 → May 2026 overdue gram-negative bacterial infections Tan Tock Seng Hospital Recruiting No outcome recorded
Phase 4 NCT04948463 Nov 2021 → Dec 2025 neutropenia Murdoch Childrens Research Institute Completed No outcome recorded
Phase 4 NCT03891979 Jun 2019 → Jun 2020 malignant pancreatic neoplasm NYU Langone Health Withdrawn No outcome recorded
Phase 4 NCT03347461 Oct 2018 → Jun 2019 discharging ear, otitis media with effusion Boston Medical Center Withdrawn No outcome recorded
Phase 4 NCT03692715 Sep 2018 → Dec 2024 nephrolithiasis, ureterolithiasis Clinical Urology and Epidemiology Working Group Completed No outcome recorded
Phase 4 NCT04456712 Jun → Nov 2018 Beni-Suef University Completed No outcome recorded
Phase not applicable29 trials
NCT07239739 Jun → Nov 2026 expected periapical periodontitis Faiz ur rahman Not yet recruiting No outcome recorded
NCT07552870 Jan → Apr 2026 cirrhosis of liver Shahida Islam Medical Complex Completed No outcome recorded
NCT07188935 Oct 2024 → Jun 2025 type 2 diabetes mellitus Al-Mustansiriyah University Completed No outcome recorded
NCT07123792 Jun 2024 → May 2025 periodontal disorder HITEC-Institute of Medical Sciences Completed No outcome recorded
NCT06158451 Mar → Aug 2024 periapical periodontitis Cairo University Unknown No outcome recorded
NCT05750966 Jul 2023 → Apr 2026 cholangitis Academic Medical Center - University of Amsterdam Completed No outcome recorded
NCT04678869 Jun 2022 → Jan 2028 expected acute lymphoblastic leukemia University College, London Active not recruiting No outcome recorded
NCT05286931 Mar 2022 → Dec 2025 overdue gonorrhea University of Washington Recruiting No outcome recorded
NCT05024188 Jan → Jul 2022 Assaf Harofeh MC Unknown No outcome recorded
NCT04593238 Nov 2020 → Apr 2021 Cairo University Unknown No outcome recorded
Also used as a comparator or background therapy in 157 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 07 trials
Phase 0 NCT05100654 Comparator Apr 2022 → Dec 2027 expected erectile dysfunction, prosthesis-related infectious disease University of Chicago Active not recruiting No outcome recorded
Phase 0 NCT05442736 Comparator Apr 2022 infectious disease British University In Egypt Completed No outcome recorded
Phase 0 NCT06149676 Background Feb 2022 → Dec 2024 urinary tract infection Ann & Robert H Lurie Children's Hospital of Chicago Completed No outcome recorded
Phase 0 NCT03326050 Comparator Feb → Sep 2018 rhinoscleroma Assiut University Unknown No outcome recorded
Phase 0 NCT02326103 Comparator Apr 2015 → Jan 2017 alcoholic hepatitis, alcoholic liver cirrhosis University of Helsinki Completed No outcome recorded
Phase 119 trials
Phase 1 NCT06810583 Background May 2025 → Sep 2030 expected acute myeloid leukemia, childhood acute lymphoblastic leukemia St. Jude Children's Research Hospital Recruiting No outcome recorded
Phase 1 NCT05959616 Background Jan 2025 → Apr 2026 overdue shigellosis University of Oxford Recruiting No outcome recorded
Phase 1 NCT05844735 Comparator May → Oct 2023 rheumatoid arthritis Sanofi Completed No outcome recorded
Phase 1 NCT05431673 Comparator Aug 2022 → Jun 2023 rhinoscleroma Assiut University Unknown No outcome recorded
Phase 1 NCT05436678 Comparator Jul → Aug 2022 NeuroSense Therapeutics Ltd. Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT02036528 Background Jan → Dec 2014 ulcer of lower limbs Royer Biomedical, Inc. Terminated No outcome recorded
Phase 1/2 NCT00872209 Comparator May → Oct 2009 otitis externa Otic Pharma Completed No outcome recorded
Phase 226 trials
Phase 2 NCT07150065 Comparator Feb → Aug 2025 typhoid fever Avicenna Medical College Lahore Completed No outcome recorded
Phase 2 NCT04791579 Comparator Feb 2025 → Mar 2027 expected urinary tract infection University of Alberta Recruiting No outcome recorded
Phase 2 NCT06368804 Background Sep 2024 → Mar 2025 overdue bronchiectasis Centre Hospitalier Intercommunal Creteil Recruiting No outcome recorded
Phase 2 NCT06185543 Comparator Nov 2023 → Sep 2025 Alzheimer disease NeuroSense Therapeutics Ltd. Terminated No outcome recorded
Phase 2 NCT05357950 Comparator May 2022 → Nov 2023 amyotrophic lateral sclerosis NeuroSense Therapeutics Ltd. Completed No outcome recorded
Phase 2/36 trials
Phase 2/3 NCT07202091 Background May 2025 → Mar 2027 expected leukemia, non-Hodgkin lymphoma, plasma cell myeloma Monash University Recruiting No outcome recorded
Phase 2/3 NCT06821763 Comparator May → Oct 2025 overdue periodontitis, pulpitis Komal Ashraf Khan Not yet recruiting No outcome recorded
Phase 2/3 NCT06006663 Comparator Aug → Oct 2023 Tanta University Unknown No outcome recorded
Phase 2/3 NCT04204954 Background May → Nov 2019 cataract, demodicidosis, mite infestation Hospital de La Luz Completed No outcome recorded
Phase 2/3 NCT04030741 Comparator Sep 2018 → Dec 2019 appendicitis King Edward Medical University Completed No outcome recorded
Phase 334 trials
Phase 3 NCT07483736 Comparator Mar 2026 → Mar 2028 expected Versailles Hospital Not yet recruiting No outcome recorded
Phase 3 NCT06055257 Background Jan 2025 → Dec 2027 expected osteoradionecrosis of the mandible Sunnybrook Health Sciences Centre Recruiting No outcome recorded
Phase 3 NCT06443502 Background Nov 2024 → Dec 2029 expected pouchitis Takeda Recruiting No outcome recorded
Phase 3 NCT03630081 Background Jan 2024 → Jan 2026 acute pyelonephritis Wockhardt Unknown No outcome recorded
Phase 3 NCT05224401 Comparator May 2023 → Sep 2027 expected bacterial urinary tract infection Lund University Recruiting No outcome recorded
Phase 438 trials
Phase 4 NCT07625267 Comparator Jul 2026 → Jun 2028 expected diverticulitis of colon Montefiore Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07590648 Background Jun 2026 → Jul 2028 expected bacterial infectious disease, childhood malignant neoplasm, hematopoietic and lymphoid cell neoplasm, neutropenia Hospital Universitari Vall d'Hebron Research Institute Not yet recruiting No outcome recorded
Phase 4 NCT07236944 Comparator Dec 2025 → Mar 2029 expected bacterial urinary tract infection Uppsala University Recruiting No outcome recorded
Phase 4 NCT07016165 Comparator Jun → Nov 2025 overdue acute lymphoblastic leukemia, acute myeloid leukemia, neutropenia Gadjah Mada University Recruiting No outcome recorded
Phase 4 NCT06093191 Comparator Oct 2023 → Oct 2025 Pseudomonas aeruginosa infectious disease, bronchiectasis Shanghai Pulmonary Hospital, Shanghai, China Completed No outcome recorded
Phase not applicable25 trials
NCT06926322 Comparator Oct 2025 → Aug 2027 expected dental pulp necrosis, neuropathy, painful, root resorption Ain Shams University Enrolling by invitation No outcome recorded
NCT06517264 Comparator Nov 2024 → Apr 2026 overdue diverticulitis of colon Monica Mengual Ballester Enrolling by invitation No outcome recorded
NCT06080698 Comparator Feb 2024 → May 2027 expected gram-negative bacterial infections Johns Hopkins University Recruiting No outcome recorded
NCT05677945 Background Mar 2023 → Mar 2024 dental pulp necrosis Cairo University Unknown No outcome recorded
NCT06174909 Comparator Nov 2022 → Aug 2023 Pakistan Institute of Medical Sciences Completed No outcome recorded

Evidence & citations 34 cited values

Every value below carries the sentence it was read from. 322 sources stand behind the page.

FieldValueCited text
Known as CIPROFLOXACIN “Patients will be provided with amoxycillin/clavulanic acid 1750-2000mg/250mg and ciprofloxacin 750 mg to keep at home for initial use if symptoms of infection develop, with...” NCT07202091
315

“oral antibiotic (eg, doxycycline, ciprofloxacin, cefadroxil, amoxicillin/clavulanic acid), topical steroid (hydrocortisone cream), topical antibiotic (clindamycin), oral...” NCT00332163

“Patients not already receiving a therapeutic antibiotic will be prescribed cefotaxime 1g six-hourly or ceftriaxone 1g daily, with dose adjusted as appropriate for organ...” NCT02389036

“OBJECTIVE: To evaluate the efficacy and safety of topical ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution relative to ciprofloxacin, 0.3%, otic solution...” PMID 28006041 Apr 2017

“The purpose of this study is to compare the relative bioavailability of ciprofloxacin 1000 mg ER tablets of Dr.Reddy's with that of CIPRO® XR 1000 mg of Bayer Pharmaceuticals...” NCT01372358

“This therapy is usually one of the following oral medications: (i) sulfamethoxazole/trimethoprim (SMX-TMP), (ii) clindamycin (Clindesse), (iii) linezolid (Zyvox), (iv)...” NCT02168816

“In case of allergy to Amoxicillin-clavulanate: intravenous administration ciprofloxacin 2 times a day 400 mg and metronidazole 3 times a day 500 mg. In case of oral...” NCT01111253

“Once the child starts tolerating oral intake and becomes clinically improved, the treatment will be changed to oral ciprofloxacin (20 mg/kg/day) divided into 2 divided doses)...” NCT04030741

“Chemotherapeutic agents used are metronidazole tablets 500 mg (Flagyl®, Sanofi, Egypt), ciprofloxacin tablets 500 mg (Ciprofloxacin tablets USP 39®, European pharmaceuticals,...” NCT06158451

Ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution seems to be efficacious and safe in treating acute otitis externa (AOE) compared with ciprofloxacin,...” PMID 35834251 Jul 2022

“The purpose of this study is to assess the efficacy of 3 days of azithromycin (AZI) compared to 3 days of ciprofloxacin (CIP) (standard-of-care) for the treatment of children...” NCT03854929

“Anti-STI regimen: ciprofloxacin 500mg orally, doxycycline 100mg BID orally 7 days and metronidazole 2g orally (cefuroxime im and/or azithromycin alternatively for pregnant and...” NCT00713999

“Double antibiotic paste (DAP): metronidazole (Flagyl, Sanofi-Aventis, Turkey) and ciprofloxacin (Cipro, Biofarma, Turkey) powdered antibiotics were stored and sealed in...” NCT05581706

“PrimeC is a fixed-dose oral combination of celecoxib and ciprofloxacin designed to target ALS-related mechanisms, including neuroinflammation, iron homeostasis, and...” PMID 41837970 May 2026

“Drug stop within 24 hours after randomization:Piperacillin-tazobactam, amikacin, meropenem, cefepime, ceftazidime, vancomycin, teicoplanin, ciprofloxacin, levofloxacine and...” NCT07590648

“* Ciprofloxacin : IV : 400mg/8h if Pseud spp ; 400mg/12h for others Gram-negative bacilli strains; PO : 1gr/12h if Pseud spp ; 750mg/12h for others Gram-negative bacilli strains” NCT05074147

“500 mg Metronidazole tablet+ 500 mg Ciprofloxacin tablet crushed into powder and mixed together with salline to form a creamy mix to be placed inside the root canal for 1 week.” NCT04593238

“It was prepared by removing the coating and crushing of antibiotic ciprofloxacin500mg,metronidazole 400mg,, and clindamycin tablets separately using a mortar and pestle.” NCT06174909

“The TAP was freshly prepared and proportioned in equal parts by volume (metronidazole, minocycline, and ciprofloxacin=1:1:1) before the scheduled treatment appointment.” NCT04547764

“A modified triple antibiotic paste consisting of ciprofloxacin, metronidazole, and clindamycin (1:1:1 by weight) will be placed in the canal using a Lentulo spiral.” NCT07123792

“mix metronidazole, ciprofloxacin and minocycline in ratio 1:1:1 with normal saline and placed as intra canal medicament during first visit of root canal treatment.” NCT06821763

“The fluroquinolones employed in the present study are referred to as oral levofloxacin (500mg q.d.), moxifloxacin (400mg, q.d.) and ciprofloxacin (500mg, b.i.d.).” NCT01761214

“During endoscopies after imaging, the anastomosis will be lavaged with an antibiotic solution composed of metronidazole, ciprofloxacin and neomycin” NCT02682485

“Zosyn will be administered unless the patient has a penicillin allergy, in which case patients will receive both ciprofloxacin and metronidazole.” NCT03159754

“Hoshino et al. recommended a ratio of 1:1:1 of metronidazole (500 mg), minocycline (100 mg) and ciprofloxacin (200 mg) for the 3Mix formulation” NCT03763110

ciprofloxacin, metronidazole \& minocycline mixed to a 1:1:1 powder used as a intracanal medicament for disinfection and cell proliferation.” NCT00881907

“2 tablets of PrimeC administered twice daily (4 tablets a day), total daily dose of 1360 mg ciprofloxacin and 136 mg celecoxib orally.” NCT06185543

“a single-dose intratympanic, intraoperative, thermosensitive, otic suspension of ciprofloxacin (OTO-201) in children requiring TTP.” PMID 26985629 May 2016

“The antibiotic would be selected from Levaquin, Vancomycin, Gentamicin, Ciprofloxacin, Mupirocin, and Trimethoprim/Sulfamethoxazole” NCT03303677

“Intracanal medicament paste composed of Ciprofloxacin, Metronidazole, and Minocycline. Placed in the root canal for several weeks.” NCT07239739

“The antibiotic regimen will consist of: oral vancomycin 250 mg qid, ciprofloxacin 500 mg bid, and metronidazole 500 mg tid.” NCT04238091

“pulp treatment with applying 3mixture of antibiotic (Metronidazole, cefixime, and Ciprofloxacin) along with simvastatin” NCT06478940

“Penicillin allergy: Ciprofloxacin 500 mg, one tablet every 12 hours + Metronidazole 500 mg, two tablets every 8 hours.” NCT06517264

“For children younger than 7 years: PO Ciprofloxacin 10mg per Kg twice a day (up to 250mg twice a day) for 3 weeks” NCT02033408

“The material is a combination of 3Mix (cefixime, metronidazole, and ciprofloxacin) and a statin (Simvastatin).” NCT06925490

ciprofloxacin and metronidazole powder mixed at a 1:1 ratio used as a intracanal medicament for disinfection.” NCT00881491

“Includes antibiotics such as amoxicillin, cephalexin, ciprofloxacin, and trimethoprim-sulfamethoxazole.” NCT06080698

“The triple antibiotic paste will be prepared using metronidazole , ciprofloxacin and doxycycline .” NCT05445362

“Group 1 (Control): LSTR using Triple Antibiotic Paste (Ciprofloxacin + Metronidazole + Cefixime).” NCT07264842

“oral quinolone (ciprofloxacin or levofloxacin) or oral macrolide (azithromycin or clarithromycin)” NCT03220074

“A total of 10 intrauterine infusions of 3ml of ciprofloxacin at a concentration of 200 mg/100 ml” NCT05205993

ciprofloxacin metronidazole minocycline paste will be :placed in the canal and kept for 4 weeks.” NCT04319575

“then Ciprofloxacin was used instead and started within 120 minutes of the procedure at 400mg IV” NCT02579161

“Drugs used would be anything from: zosyn, ciprofloxacin or ceftriaxone and flagyl, augmentin” NCT05724628

“and ciprofloxacin 750 mg to keep at home for initial use if symptoms of infection develop” NCT07202052

“The fluoroquinolone antibiotics included ciprofloxacin, levofloxacin, and moxifloxacin.” NCT04879030

“intrauterine infusion of 3ml of ciprofloxacin at a concentration of 200 mg/100 ml” NCT04447625

“* Active substance: Ciprofloxacin 0.3% * Pharmaceutical form: Ophthalmic solution” NCT03519516

“DAP is a combination of two antibiotics which are ciprofloxacin and metronidazole” NCT05600023

“PRP (nafcillin or flucloxacillin) or vancomycin, plus aztreonam or ciprofloxacinNCT00303589

“broad spectrum antibiotics (vancomycin, ciprofloxacin, metronidazole) for 7 days” NCT03051698

Ciprofloxacin, metronidazole, vancomycin, amoxicillin clavulanate or rifaximin.” NCT06443502

“3-mixtatin mixture of ciprofloxacin, metronidazole, cefixime, and simvastatin” NCT03084601

“Drug: Ciprofloxacin 500 mg, po, twice daily for 7 days (Other Names: Cipro)” NCT01731236

“fosfomycin 3g once oral, ciprofloxacin 250 mg oral twice a day for 5 days” NCT07686055

“Ciprodex (0.3% Ciprofloxacin and Dexamethasone 0.1% Otic Suspension)” NCT01359098

Ciprofloxacin, 500 mg 2/day \& Metronidazole (Flagyl), 500 mg 3/day.” NCT05024188

“Oral antibiotics: 1) ciprofloxacin, 2) trimethoprim-sulfamethoxazole” NCT07236944

“1:1 metronidazole and ciprofloxacin are mixed with propylene glycol” NCT05079802

Ciprofloxacin and Metronidazol will be used as oral antibiotics” NCT01572558

“tienam,meropenem,levofloxacin,ciprofloxacin,amikacin,gentamicin” NCT03622450

Ciprofloxacin 500 mg per os once at months 2, 3, 5, 6, 8 and 9” NCT01329588

Ciprofloxacin 1000 mg Tablets Dr. Reddy's Laboratories Limited” NCT01372345

Ciprofloxacin (Ciprocin 250 mg tablets; EPICO, Cairo, Egypt)” NCT03533231

ciprofloxacin (Cipro, 750 mg tablets, Biofarma, Turkiye)” NCT06818578

“an oral fluoroquinolone (ciprofloxacin 750mg tw/d)” NCT06368804

ciprofloxacin 250 mg oral twice a day for 5 days” NCT05726318

“Arm 1: ciprofloxacin 500 mg once pre-procedure” NCT05719285

“clindamycin, ciprofloxacin and metronidazole” NCT06006663

“1 g ciprofloxacin (500 mg morning and night)” NCT06055257

Ciprofloxacin, Metronidazole, & Minocycline” NCT01976065

“20 mg/kg of the antibiotic, ciprofloxacin.” NCT06149676

“* Ciprofloxacin IV and PO 750to 1000mg/12h” NCT02123628

Ciprofloxacin or Rifaximin for 10 days.” NCT04003181

Ciprofloxacin 500 mg, twice daily;” NCT04150250

“500 mg Ciprofloxacin twice daily” NCT05384197

Ciprofloxacin 400 mg IV/12h” NCT02795949

“500 mg Ciprofloxacin tab” NCT05677945

Ciprofloxacin*” NCT02099240

ciprofloxacinNCT06149676

CiprofloxacinNCT05846399

ciprofloxacinNCT05750966

NCT01803191

NCT02773732

NCT01515007

NCT00722735

NCT05959616

NCT00139230

NCT02340182

NCT02036528

NCT01772615

NCT04870138

NCT02173262

NCT04698057

NCT07150065

NCT00142272

NCT02800785

NCT02068846

NCT03027635

NCT05162625

NCT00438269

NCT01168895

NCT01538667

NCT00153634

NCT01789203

NCT01505634

NCT00760032

NCT03939273

NCT03327844

NCT02458781

NCT01052298

NCT04090684

NCT00609973

NCT00654108

NCT00649662

NCT02127749

NCT00930982

NCT03850379

NCT04948463

NCT00761462

NCT07625267

NCT04444440

NCT03692715

NCT04110340

NCT02304822

NCT01072942

NCT00910351

NCT06234046

NCT01753115

NCT01768663

NCT02216071

NCT01137903

NCT02600559

NCT02717871

NCT00194532

NCT04552431

NCT03507556

NCT00355602

NCT01243437

NCT00392275

NCT01659866

NCT07552870

NCT00741052

NCT03643198

NCT02326103

NCT01749605

NCT00004216

NCT06798402

NCT03228108

NCT03716804

NCT01785641

NCT00367913

NCT02947763

NCT05442736

NCT02423759

NCT00945802

NCT00736983

NCT02261896

NCT04456712

NCT03177720

NCT04791579

NCT00445497

NCT02944825

NCT03840811

NCT02104245

NCT00481689

NCT00138411

NCT00676533

NCT02801370

NCT02961751

NCT05398679

NCT03326050

NCT03012360

NCT02719158

NCT05844735

NCT07704359

NCT00688272

NCT07483736

NCT04678869

NCT00650351

NCT02734732

NCT07016165

NCT00002850

NCT01929460

NCT02196740

NCT05286931

NCT05431673

NCT03357614

NCT02358993

NCT06342830

NCT00645788

NCT01599806

NCT00649155

NCT06093191

NCT01756924

NCT05678621

NCT00596453

NCT01344512

NCT00809913

NCT07616635

NCT03985514

NCT01908803

NCT04549311

NCT02252978

NCT01783106

NCT00964561

NCT00873626

NCT05287425

NCT01873690

NCT00668044

NCT02357407

NCT07188935

NCT01059890

NCT00190151

NCT07028424

NCT03262142

NCT03862170

NCT00719056

NCT04067011

NCT01733966

NCT01561794

NCT00003824

NCT00257699

NCT05863832

NCT03358576

NCT02765256

NCT03173053

NCT03891979

NCT05804123

NCT01265173

NCT01208922

NCT01952444

NCT02620007

NCT01649635

NCT00651586

NCT00669994

NCT00889967

NCT05462496

NCT02114671

NCT00668122

NCT02724046

NCT05294588

NCT04204954

NCT05977868

NCT05843708

NCT00832286

NCT01108601

NCT02300220

NCT02247960

NCT04147260

NCT03969758

NCT01928433

NCT02011841

NCT01279252

NCT01595438

NCT02015507

NCT00137787

NCT00107081

NCT02598362

NCT00980876

NCT00992329

NCT06926322

NCT00670215

NCT02375295

NCT04575493

NCT02118909

NCT05274672

NCT03366207

NCT01386593

NCT04165850

NCT01400750

NCT01157819

NCT00598403

NCT03630081

NCT02223338

NCT05232461

NCT00062231

NCT00840294

NCT05100654

NCT05385887

NCT00872209

NCT02532192

NCT00805558

NCT01723150

NCT03354598

NCT04636957

NCT06728072

NCT00961038

NCT00785980

NCT02816112

NCT03431675

NCT04763070

NCT01888822

NCT06126731

NCT00791505

NCT04523987

NCT02790138

NCT06810583

NCT00000641

NCT05199324

NCT06709196

NCT00126698

NCT00590785

NCT07113587

NCT05224401

NCT02505581

NCT05436678

NCT03854929

NCT01542801

NCT01402947

NCT00097773

NCT01124799

NCT01764841

NCT04374188

NCT02106832

NCT03476317

Known as Amox-clav Amox-clav given to eligible women as per existing protocol, which is 625mg three times a day, for a week” NCT03459599
Known as Amoxycillin + Clavulanic acid “None of the authors have received any form of honoraria, funding, grant, employment or have financial interest in the manufacturer of Co-Amoxiclav™ (Amoxycillin + Clavulanic...” PMID 31296180 Jul 2019
1

“Three hospitals where the current protocol was to administer prophylactic amoxycillin-clavulanic acid served as the sites of recruitment.” PMID 31296180 Jul 2019

Known as ARD-3150 “In the recent phase-3 ORBIT trials, 48 weeks' treatment with ARD-3150 (inhaled liposomal ciprofloxacin) did not significantly improve symptoms” PMID 32554534 Oct 2020
Known as BAYO9867 “Ciprofloxacin (BAYO9867)” NCT00668044
Known as BAYQ3939 “Ciprofloxacin (BAYQ3939) dry powder for inhalation” NCT02106832
13

“Ciprofloxacin (Cipro InhaIe, BAYQ3939)” NCT01072942

“Ciprofloxacin (Cipro Inhale, BAYQ3939)” NCT00645788

“Cipro Inhale (Ciprofloxacin, BAYQ3939)” NCT01168895

“Ciprofloxacin (Cipro inhale, BAYQ3939)” NCT01052298

“Ciprofloxacin (Cipro Inhale, BAYQ3939)” NCT01538667

“Ciprofloxacin (PulmoSphere, BAYQ3939)” NCT00961038

“Cipro XR (Ciprofloxacin, BAYQ3939)” NCT00668122

“Cipro XR (Ciprofloxacin, BAYQ3939)” NCT00481689

“Drug: Ciprofloxacin DPI (BAYQ3939)” NCT01764841

“Cipro XR (Ciprofloxacin, BAYQ3939)” NCT00676533

“Ciprofloxacin (Cipro, BAYQ3939)” NCT00930982

“Ciprofloxacin (Cipro, BAYQ3939)” NCT01561794

“Ciprofloxacin (Cipro, BAYQ3939)” NCT00910351

Known as Ciloxan “Groups 1, 2 and 3 received topical ofloxacin 0.3% (Ocuflox), ciprofloxacin 0.3% (Ciloxan) and levofloxacin (Quixin) respectively;” PMID 18211932 Jan 2008
Known as CIP “The purpose of this study is to assess the efficacy of 3 days of azithromycin (AZI) compared to 3 days of ciprofloxacin (CIP) (standard-of-care) for the treatment of children...” NCT03854929
1

Ciprofloxacin hydrochloride (CIP) in chitosan coated PLGA nanoparticles (CIP-CS-PLGA-NPs) and free CIP were embedded in Pluronic® 407/188 to form thermosensitive gels(F1) and...” NCT05442736

Known as Cipro “Double antibiotic paste (DAP): metronidazole (Flagyl, Sanofi-Aventis, Turkey) and ciprofloxacin (Cipro, Biofarma, Turkey) powdered antibiotics were stored and sealed in...” NCT05581706
8

“Intravenous and oral antibiotics without surgery Piperacillin/Tazobactam and then Augmentin Cipro/Flagyl if Penicillin allergic” NCT02189668

“Drug: Ciprofloxacin 500 mg, po, twice daily for 7 days (Other Names: Cipro)” NCT01731236

“All subjects will be treated with Cipro, an antibiotic, for 5 days.” NCT00654108

ciprofloxacin (Cipro, 750 mg tablets, Biofarma, Turkiye)” NCT06818578

“Group 1: Topical 0.3% Ciprofloxacin [Cipro]” NCT04204954

Ciprofloxacin (Cipro, BAYQ3939)” NCT00930982

Ciprofloxacin (Cipro, BAYQ3939)” NCT01561794

Ciprofloxacin (Cipro, BAYQ3939)” NCT00910351

Known as Cipro InhaIe “Ciprofloxacin (Cipro InhaIe, BAYQ3939)” NCT01072942
Known as Cipro inhale “Ciprofloxacin (Cipro inhale, BAYQ3939)” NCT01052298
3

“Ciprofloxacin (Cipro Inhale, BAYQ3939)” NCT01538667

Cipro Inhale (Ciprofloxacin, BAYQ3939)” NCT01168895

“Ciprofloxacin (Cipro Inhale, BAYQ3939)” NCT00645788

Known as Cipro IR Cipro IR (Ciprofloxacin, BAYQ3939)” NCT00668122
Known as CIPRO IV “Ciprofloxacin 400 MG/200 ML Intravenous Solution [CIPRO IV]” NCT05162625
Known as Cipro XR Cipro XR (Ciprofloxacin, BAYQ3939)” NCT00668122
4

Cipro XR (Ciprofloxacin, BAYQ3939)” NCT00481689

Cipro XR (Ciprofloxacin, BAYQ3939)” NCT00676533

“Cipro® XR Tablets 1000 mg” NCT00649662

“Cipro® XR Tablets (500 mg” NCT00649155

Known as Ciprocin “Ciprofloxacin (Ciprocin 250 mg tablets; EPICO, Cairo, Egypt)” NCT03533231
Known as Ciprofloxacin (Cetraxal) Ciprofloxacin (Cetraxal)NCT02168816
Known as ciprofloxacin (Cifran) ciprofloxacin (Cifran)NCT01761214
Known as Ciprofloxacin hydrochloride Ciprofloxacin hydrochloride (CIP) in chitosan coated PLGA nanoparticles (CIP-CS-PLGA-NPs) and free CIP were embedded in Pluronic® 407/188 to form thermosensitive gels(F1) and...” NCT05442736
Known as Ciprofloxacin Inhale Ciprofloxacin Inhale 50 and 75 mg 2 times a day (BID) for 10 days” NCT01072942
Known as Ciprofloxacin Ophthalmic solution Ciprofloxacin Ophthalmic solutionNCT03519516
Known as Ciprofloxacin tablets USP 39 “Chemotherapeutic agents used are metronidazole tablets 500 mg (Flagyl®, Sanofi, Egypt), ciprofloxacin tablets 500 mg (Ciprofloxacin tablets USP 39®, European pharmaceuticals,...” NCT06158451
Known as Ciproxin “Intralesional ciprofloxacin (2 mg/ml, 100 ml, Ciproxin®, Bayer Schering pharma AG, Germany), each lesion was injected based on lesion size (2 mg/cm2).” NCT06798402
Known as Ciproxin - ciprofloxacin “Ciproxin ® - ciprofloxacin” NCT01400750
Known as Co-Amoxiclav “None of the authors have received any form of honoraria, funding, grant, employment or have financial interest in the manufacturer of Co-Amoxiclav™ (Amoxycillin + Clavulanic...” PMID 31296180 Jul 2019
Known as CPFX “Ciprofloxacin (CPFX) is a potential alternative in patients with febrile neutropenia (FN) because of its activity against Gram-negative organisms.” PMID 23317527 Jan 2013