drugset / Trial / NCT00881907
Tissue Characterization in Teeth Treated With a Regeneration Protocol
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of the investigators study is to characterize the composition of the hard and soft tissues present in root canals of teeth previously diagnosed with necrotic pulps and incomplete root formation and treated with a triple antibiotic regeneration protocol. The investigators hypothesis is that treatment of teeth with necrotic pulps and immature apices with triple antibiotic paste will stimulate continued root formation by the deposition of dentin at the root apices. The primary outcome measure will be histological identification of mineralized tissue and adherent cells in the apical third of these teeth.
Timeline
- Start
- 2010-03
- Primary completion
- 2014-03
- Completion
- 2014-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ciprofloxacin | Small molecule | — | — |
| Subject | Metronidazole | Small molecule | — | — |
| Subject | Minocycline | Small molecule | — | — |