drugset / Trial / NCT00002850
Antibiotic Therapy in Preventing Early Infection in Patients With Multiple Myeloma Who Are Receiving Chemotherapy
Phase 3
Completed
212 enrolled
Gary Morrow
Eastern Cooperative Oncology Group · collabNational Cancer Institute (NCI) · collab
RandomizedParallel-groupOpen-labelSupportive care
Summary
RATIONALE: Giving antibiotics may be effective in preventing or controlling early infection in patients with multiple myeloma and may improve their response to chemotherapy. PURPOSE: This randomized clinical trial is studying antibiotics to see how well they work compared to no antibiotics in preventing early infection in patients with multiple myeloma.
Timeline
- Start
- 1997-03
- Primary completion
- 2011-04
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ciprofloxacin | Small molecule | 500 mg | Oral |
| Subject | Ofloxacin | Small molecule | 400 mg | Oral |
| Subject | Ofloxacin | Small molecule | 500 mg | Oral |
| Subject | Sulfamethoxazole | Small molecule | 800 mg | Oral |
| Subject | Trimethoprim | Small molecule | 160 mg | Oral |