Population Pharmacokinetics of Anti-infectious Drugs in Children

Completed 214 enrolled University Hospital, Bordeaux

RandomizedParallel-groupOpen-labelTreatment

Summary

The Pharm A project is a French national collaborative project aiming to determine the population pharmacokinetics of ceftazidime, ciprofloxacin, and voriconazole in paediatric patients aged one month to five years.

Timeline

Start: 2011-06
Primary completion: 2014-09
Completion: 2014-09

Publications

Bui S, Facchin A, Ha P, Bouchet S, Leroux S, Nacka F, Fayon M, Jacqz-Aigrain E. Population pharmacokinetics of ceftazidime in critically ill children: impact of cystic fibrosis. J Antimicrob Chemother. 2020 Aug 1;75(8):2232-2239. doi: 10.1093/jac/dkaa170.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ceftazidime	Small molecule	—	Intravenous
Subject	Ciprofloxacin	Small molecule	—	—
Subject	Voriconazole	Small molecule	—	—

Indications

No indication recorded.