drugset / Trial / NCT04447625

Intrauterine Antibiotic Infusion in Treating Chronic Endometritis and Restoring Reproductive Dynamics

NCT04447625

Phase 2 Completed 80 enrolled Genesis Athens Clinic
RandomizedParallel-groupOpen-labelTreatment

Summary

Chronic Endometritis (CE) is related to infertility and entails a challenging management. This study investigates the treatment of off-label intrauterine antibiotic infusion (IAI) combined with oral antibiotic administration (OAA), and it assesses respective performance against the gold standard treatment of OAA. Data sourced herein reports on treatment efficiency and fertility restoration for both patients aiming to conceive naturally or via In Vitro fertilization (IVF).

Timeline

Start
2017-03-01
Primary completion
2019-02-28
Completion
2020-01-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Ciprofloxacin Small molecule 3 ml Other
Subject Doxycycline Small molecule 100 mg Oral
Subject Metronidazole Small molecule 500 mg Oral

Indications