drugset / Trial / NCT05079802

Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles

NCT05079802

Phase 3 Unknown 36 enrolled Ain Shams University
RandomizedParallel-groupDouble-blindTreatment

Summary

LSTR will be done for primary teeth with significant root resorption needing non-vital pulp therapy to save such teeth for up to 12 months. The first part will be in vitro study to compare the antimicrobial effect of double antibiotic paste mixed with chitosan nanoparticle vs double antibiotic paste mixed with propylene glycol. The second part will be randomized clinical trial comparing the clinical and radiographic success of LSTR in study group where double antibiotic mix is mixed with chitosan nanoparticles and control group where double antibiotic paste is mixed with propylene glycol .

Timeline

Start
2021-12-01
Primary completion
2023-12-31
Completion
2024-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Ciprofloxacin Small molecule
Subject Metronidazole Small molecule

Indications