drugset / Trial / NCT02118909

Evaluate the Effects of Itraconazole and Ciprofloxacin on Single-Dose PK of Pracinostat in Healthy Nonsmoking Subjects

NCT02118909

Phase 1 Completed 32 enrolled Helsinn Healthcare SA
RandomizedParallel-groupOpen-labelOther

Summary

This study is designed as a 2-part, open-label study to assess the effect of pracinostat with itraconazole (part 1) and pracinostat with ciprofloxacin (part 2) on the bioavailability of pracinostat. Secondarily to evaluate the safety and tolerability of pracinostat administered with itraconazole or ciprofloxacin.

Timeline

Start
2014-05
Primary completion
2014-06
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Ciprofloxacin Small molecule
Subject Itraconazole Small molecule
Subject Pracinostat Other / unclassified

Indications

No indication recorded.