Drugs / Pracinostat

Trials 16 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT02058784 Feb → Mar 2014 Helsinn Healthcare SA Completed No outcome recorded
Phase 16 trials
Phase 1 NCT03848754 May 2019 → May 2021 acute myeloid leukemia Medical College of Wisconsin Completed No outcome recorded
Phase 1 NCT03495934 Feb 2018 Helsinn Healthcare SA Completed No outcome recorded
Phase 1 NCT02118909 May → Jun 2014 Helsinn Healthcare SA Completed No outcome recorded
Phase 1 NCT01184274 Oct 2010 → Apr 2012 cancer, leukemia NCIC Clinical Trials Group Completed No outcome recorded
Phase 1 NCT00504296 Sep 2007 → Apr 2010 NCIC Clinical Trials Group Completed No outcome recorded
Phase 1 NCT00741234 Apr 2007 → Mar 2012 cancer, hematopoietic and lymphoid cell neoplasm, myelodysplastic syndrome S*BIO Completed No outcome recorded
Phase 28 trials
Phase 2 NCT03151304 Jun 2017 → Dec 2020 myelodysplastic syndrome Helsinn Healthcare SA Terminated No outcome recorded
Phase 2 NCT02267278 Jan 2015 → Jun 2018 myeloproliferative neoplasm M.D. Anderson Cancer Center Completed No outcome recorded
Phase 2 NCT01912274 Dec 2013 → Nov 2016 acute myeloid leukemia Helsinn Healthcare SA Completed No outcome recorded
Phase 2 NCT01993641 Dec 2013 → May 2015 myelodysplastic syndrome Helsinn Healthcare SA Completed No outcome recorded
Phase 2 NCT01873703 Jun 2013 → Nov 2015 myelodysplastic syndrome Helsinn Healthcare SA Completed No outcome recorded
Phase 2 NCT01200498 Nov 2010 → Nov 2012 myeloproliferative neoplasm M.D. Anderson Cancer Center Completed No outcome recorded
Phase 2 NCT01112384 Oct 2010 → Jan 2013 sarcoma NCIC Clinical Trials Group Completed No outcome recorded
Phase 2 NCT01075308 Jun 2010 → Jan 2015 prostate cancer NCIC Clinical Trials Group Completed No outcome recorded
Phase 31 trial
Phase 3 NCT03151408 Jun 2017 → Aug 2020 acute myeloid leukemia Helsinn Healthcare SA Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as pracinostat Pracinostat (SB939) is a potent oral inhibitor of class 1, 2, and 4 histone deacetylases (HDAC).” PMID 23893953 Jul 2013
10

NCT02058784

NCT01993641

NCT02267278

NCT03848754

NCT03151304

NCT01873703

NCT01912274

NCT03495934

NCT03151408

NCT02118909

Known as SB939 “Pracinostat (SB939) is a potent oral inhibitor of class 1, 2, and 4 histone deacetylases (HDAC).” PMID 23893953 Jul 2013
5

NCT01075308

NCT00741234

NCT00504296

NCT01200498

NCT01112384

Action Inhibit “RATIONALE: SB939 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.” NCT00504296
Modality Other / unclassified “Histone deacetylase inhibitor (HDACi)” NCT01873703
Route Oral “OUTLINE: Patients receive oral SB939 once daily on days 1-5 and 15-19.” NCT00504296