drugset / Trial / NCT07686055

Precision Management of Urinary Tract Symptoms in Older Women

NCT07686055

RandomizedParallel-groupOpen-labelTreatment

Summary

This project aims to improve the diagnosis and management of urinary tract symptoms in older women by comparing three common treatment strategies-empiric antibiotics, urinalysis-guided therapy, and culture-directed care-in a randomized trial. By integrating patient-reported outcomes, laboratory data, the study will identify which patients benefit from antibiotics and which can safely avoid them. Findings will inform precision care strategies and promote antibiotic stewardship while improving symptom outcomes and quality of life in this high-risk population.

Timeline

Start
2026-07-14
Primary completion
2027-02-01
Completion
2027-02-14

Drugs

EvaluationDrugModalityDoseRoute
Subject CEPHALEXIN ANHYDROUS Small molecule 500 mg Oral
Subject Ciprofloxacin Small molecule 250 mg Oral
Subject Fosfomycin Small molecule 3 g Oral
Subject Nitrofurantoin Unknown 100 mg Oral
Subject trimethoprim/sulfamethoxazole Unknown 125 mg Oral
Subject trimethoprim/sulfamethoxazole Unknown 875 mg Oral