drugset / Trial / NCT07836686

CLINICAL AND RADIOGRAPHIC SUCCESS OF MODIFIED LSTR TECHNIQUES IN PRIMARY SECOND MOLARS

NCT07836686 ↗

Completed 64 enrolled Uşak University
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study aimed to evaluate and compare the clinical and radiographic success of different antibiotic and vehicle modifications of the Lesion Sterilization and Tissue Repair (LSTR) technique in infected mandibular primary second molars. The study included systemically healthy children aged 4-11 years. Participants were assigned to four treatment groups according to the antibiotic combination (3Mix or 2Mix) and vehicle used \[Macrogol-Propylene Glycol (MP) or normal saline (NS)\]: 3Mix-MP, 3Mix-NS, 2Mix-MP, and 2Mix-NS. Clinical outcomes were evaluated at 3, 6, and 12 months after treatment, and radiographic outcomes were evaluated at 6 and 12 months. The clinical and radiographic success of the four LSTR modifications was compared over the 12-month follow-up period.

Timeline

Start
2024-11-26
Primary completion
2026-03-05
Completion
2026-03-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Ciprofloxacin Small molecule — —
Subject Clindamycin Unknown — —
Subject Metronidazole Small molecule — —