Docetaxel and Hydroxychloroquine in Treating Patients With Metastatic Prostate Cancer

Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Hydroxychloroquine may help docetaxel work better and kill more tumor cells. PURPOSE: This phase II trial is studying how well giving docetaxel together with hydroxychloroquine works in treating patients with metastatic prostate cancer.

Timeline

Start

2008-12

Primary completion

2012-10

Completion

2012-10

Outcome

Outcome not reported

Stopped: “Lack of improved efficacy compared to historical controls, competing studies”

Drugs

Indications