drugset / Trial / NCT00797056

Stem Cell Mobilization by G-CSF to Treat Severe Peripheral Artery Disease

NCT00797056

Phase 0 Completed 32 enrolled Washington University School of Medicine
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study is designed to test the use of G-CSF in peripheral vascular disease. The investigators hypothesize that mobilization of angiogenic cells into the blood by granulocyte colony stimulating factor (G-CSF) may stimulate the formation of new blood vessels and result in a sustained improvement in blood flow in patients with severe peripheral arterial disease.

Timeline

Start
2008-04
Primary completion
2012-04
Completion
2012-04

Drugs

EvaluationDrugModalityDoseRoute
Subject G-CSF Unknown 5 ug/kg Subcutaneous
Background Aspirin Small molecule 75 mg
Background Clopidogrel Small molecule 75 mg