drugset / Trial / NCT00802113

Autologous and Allogeneic Transplant for Relapsed Lymphoma

NCT00802113

Phase 1/2 Completed 30 enrolled Columbia University
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The sequential combination of myeloablative therapy and autologous stem cell transplantation (APBSCT) followed by a reduced intensity allogeneic stem cell transplant (Allo SCT) and post SCT adoptive cellular immunotherapy will be well tolerated in patients with refractory or recurrent non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD).

Timeline

Start
2003-06
Primary completion
2014-10
Completion
2014-10-22

Drugs

EvaluationDrugModalityDoseRoute
Subject ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) Protein / enzyme biologic 2 mg/kg
Subject Busulfan Small molecule 3.2 mg/kg
Subject Fludarabine Small molecule 30 mg/m2