drugset / Trial / NCT00807196

Zevalin With Non Myeloablative Allogeneic Stem Cell Transplantation in Patients With Non Hodgkin Lymphoma

NCT00807196

Phase 1/2 Unknown 20 enrolled Maisonneuve-Rosemont Hospital Bayer · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to investigate the ability to combine a radioactive medication directly targeted against lymphoma cells with the immune effects of an allogeneic blood stem cell transplant.

Timeline

Start
2008-09
Primary completion
2011-12
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified 300 mg/m2 Intravenous
Subject Fludarabine Small molecule 30 mg/m2 Intravenous
Subject Rituximab Monoclonal antibody 250 mg/m2
Subject ibritumomab tiuxetan Monoclonal antibody 14.8 mbq/kg Intravenous

Indications