drugset / Trial / NCT00814593

Lymphokine-Activated Killer Cells or Gliadel Wafer in Treating Patients With Newly Diagnosed Glioblastoma Multiforme That Can Be Removed by Surgery

NCT00814593

Phase 2 Withdrawn Lisata Therapeutics, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

RATIONALE: Biological therapies, such as lymphokine-activated killer cells, may stimulate the immune system in different ways and stop tumor cells from growing. Drugs used in chemotherapy, such as Gliadel wafer, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether lymphokine-activated killer cells are more effective than Gliadel wafer in treating patients with glioblastoma multiforme. PURPOSE: This randomized phase II trial is studying the side effects and how well lymphokine-activated killer cells work compared with Gliadel wafer in treating patients with newly diagnosed glioblastoma multiforme that can be removed by surgery.

Timeline

Start
2008-11
Primary completion
2011-04
Completion
2011-09

Drugs

EvaluationDrugModalityDoseRoute
Subject carmustine Small molecule Other
Subject lymphokine-activated killer cells Cell therapy Other