drugset / Trial / NCT00814944
A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to determine the safety and efficacy of an ocular sirolimus (rapamycin) formulation compared to Placebo on the signs and symptoms of dry eye in the CAE Model.
Timeline
- Start
- 2009-04
- Primary completion
- 2009-10
- Completion
- 2009-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sirolimus | Small molecule | 220 ug | Other |
| Comparator | Sirolimus | Small molecule | 440 ug | Other |
| Comparator | Sirolimus | Small molecule | 880 ug | Other |