drugset / Trial / NCT00818701
Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction
RandomizedCrossoverTriple-blindBasic science
Summary
The purpose of the study is to show that low dose recombinant BNP coupled with phosphodiesterase V inhibition will improve renal dysfunction and promote relief of volume overload in patinets with acute decompensated heart failure complicated by the cardiorenal syndrome.
Timeline
- Start
- 2009-02
- Primary completion
- 2010-08
- Completion
- 2010-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Nesiritide | Protein / enzyme biologic | 0.005 ug/kg | Other |
| Comparator | Sildenafil | Unknown | 50 mg | — |