drugset / Trial / NCT00824564
Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture
RandomizedParallel-groupOpen-labelPrevention
Summary
Tranexamic acid has been shown to reduce postoperative blood losses and transfusion requirements in a number of types of surgery. Most trials in orthopedic surgery have been conducted in arthroplasty, hip fracture and spine surgeries. This study would aim to see the effect of tranexamic acid in reduction of blood loss and transfusions for long bone fracture surgery, primarily fracture shaft of femur.
Timeline
- Start
- 2009-04
- Primary completion
- 2010-06
- Completion
- 2010-06
Outcome
Missed primary endpoint
registry Tranexamic Acid Plus Standard of Care vs Standard of Care; p = 0.348; Mean Difference (Final Values) -55.5 (95% CI -172.7 to 61.7) NCT00824564 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tranexamic Acid | Small molecule | 15 mg/kg | Intravenous |
Indications
No indication recorded.