drugset / Trial / NCT00825266

Insulin Resistance in Pulmonary Arterial Hypertension

NCT00825266

Phase 2 Terminated 2 enrolled Stanford University
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate 1) the incidence of insulin resistance (a pre-diabetic state) in patients with pulmonary hypertension, and 2) test the utility of a validated PH therapy (Tracleer) versus Pioglitazone in the treatment of those patients found to have insulin resistance.

Timeline

Start
2008-09
Primary completion
2010-05
Completion
2010-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bosentan Other / unclassified 125 mg
Comparator Pioglitazone Small molecule 30 mg