drugset / Trial / NCT00827931
Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Major Abdominal Surgery
RandomizedParallel-groupOpen-labelPrevention
Summary
Tranexamic acid has been shown to reduce postoperative blood losses and transfusion requirements in various types of major surgery (orthopedic surgery, spine surgery, cardiopulmonary bypass, liver resections, and gynecological cancers).The current trial is being conducted to compare the efficacy of tranexamic acid plus standard of care versus standard of care in reduction of blood loss in patients undergoing major abdominal surgeries.
Timeline
- Start
- 2009-09
- Primary completion
- 2011-04
- Completion
- 2011-05
Outcome
Missed primary endpoint
registry Tranexamic Acid Plus Standard of Care vs Standard of Care; p = 0.460; Mean Difference (Final Values) -99.9 NCT00827931 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tranexamic Acid | Small molecule | 15 mg/kg | Intravenous |
Indications
No indication recorded.