drugset / Trial / NCT00830193
N-Acetylcysteine in Critically Ill Patients Undergoing Contrast Enhanced Computed Tomography
Phase 2/3
Completed
45 enrolled
Unity Health Toronto
Fran Priestap · collabMartin, Claudio M., M.D. · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Critically ill patients frequently undergo contrast enhanced computed tomography (CT) to establish diagnoses and direct management. Contrast agents can disturb kidney function and result in kidney dysfunction. The investigators investigated the effects of high dose N-acetylcysteine (NAC) or placebo, in addition to hydration, in preventing kidney dysfunction following contrast enhanced CT) in critically ill adults in the intensive care units of two teaching hospitals.
Timeline
- Start
- 2002-08
- Primary completion
- 2005-05
- Completion
- 2005-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | N-acetylcysteine | Small molecule | 10 g | Intravenous |