drugset / Trial / NCT00836082
A Multiple Dose Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04457845 in Healthy Volunteers
RandomizedParallel-groupDouble-blind
Summary
To determine if PF-04457845 at doses of 0.5mg, 1mg, 4mg, and 8 mg given once daily for 14 days will be safe and well tolerated in healthy volunteers. To determine the effect on food on PF-04457845 pharmacokinetics and safety following administration of single doses of 4mg and 8mg.
Timeline
- Start
- 2009-02
- Primary completion
- 2009-07
- Completion
- 2009-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | REDAFAMDASTAT | Small molecule | 0.5 mg | Oral |
| Subject | REDAFAMDASTAT | Small molecule | 1 mg | Oral |
| Subject | REDAFAMDASTAT | Small molecule | 4 mg | Oral |
| Subject | REDAFAMDASTAT | Small molecule | 8 mg | Oral |