drugset

drugset / Trial / NCT00837902

Genetic Determinants of Response to Beta Blockade

NCT00837902 ↗

Completed 154 enrolled Vanderbilt University National Center for Research Resources (NCRR) · collab National Heart, Lung, and Blood Institute (NHLBI) · collab

NaSingle-groupOpen-labelOther

Summary

The overall goal of this project is to determine the genetic factors contributing to interindividual differences in response to beta-blockade.

Timeline

Start: 2009-01
Primary completion: 2012-12-31
Completion: 2014-12-31

Publications

Results Kurnik D, Cunningham AJ, Sofowora GG, Kohli U, Li C, Friedman EA, Muszkat M, Menon UB, Wood AJ, Stein CM. GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans. Pharmacogenomics. 2009 Oct;10(10):1581-7. doi: 10.2217/pgs.09.92.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Atenolol	Other / unclassified	25 mg	Oral

Indications

No indication recorded.