drugset / Trial / NCT00841724

Study of a Reduced-toxicity "Submyeloablative" Conditioning Regimen Prior to Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies

NCT00841724

Phase 2 Completed 82 enrolled Nantes University Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The goal of this prospective study is to assess the overall mortality (whether related to relapse/progression or toxicity - TRM-) at one year after allogeneic stem cell transplantation prepared by a so-called reduced-toxicity "submyeloablative" conditioning regimen in patients with hematological malignancies.

Timeline

Start
2009-01
Primary completion
2012-01
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Busulfan Small molecule
Comparator Fludarabine Small molecule
Comparator Thymoglobulin Protein / enzyme biologic