Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne

Phase 4 Completed 54 enrolled Stiefel, a GSK Company GlaxoSmithKline · collab

RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of the study is to determine the development of microbial resistance when using one of two topical acne therapies for the treatment of facial acne vulgaris.

Timeline

Start: 2007-08
Primary completion: 2008-11
Completion: 2009-01

Publications

Results Jackson JM, Fu JJ, Almekinder JL. A randomized, investigator-blinded trial to assess the antimicrobial efficacy of a benzoyl peroxide 5%/ clindamycin phosphate 1% gel compared with a clindamycin phosphate 1.2%/tretinoin 0.025% gel in the topical treatment of acne vulgaris. J Drugs Dermatol. 2010 Feb;9(2):131-6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Benzoyl Peroxide	Other / unclassified	5 %	Topical
Subject	Clindamycin	Unknown	1 %	Topical
Subject	Clindamycin	Unknown	1.2 %	Topical
Subject	Tretinoin	Small molecule	0.025 %	Topical

Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne

Summary

Timeline

Publications

Drugs

Indications