drugset / Trial / NCT00847626
Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension
RandomizedFactorialQuadruple-blindTreatment
Summary
The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil combined with chlorthalidone, once daily (QD), in participants with moderate to severe hypertension.
Timeline
- Start
- 2009-01
- Primary completion
- 2010-05
- Completion
- 2010-07
Outcome
Met primary endpoint
registry Azilsartan Medoxomil 40 mg or 80 mg/Chlorthalidone 25 mg QD vs Chlorthalidone 25 mg QD; p <0.001; Mean Difference (Net) -13.0 NCT00847626 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Azilsartan medoxomil | Other / unclassified | 20 mg | Oral |
| Subject | Azilsartan medoxomil | Other / unclassified | 40 mg | Oral |
| Subject | Azilsartan medoxomil | Other / unclassified | 80 mg | Oral |
| Subject | Chlorthalidone | Other / unclassified | 12.5 mg | Oral |
| Subject | Chlorthalidone | Other / unclassified | 25 mg | Oral |