Sedation and Pain (The Effect of IV Sedation on Pain Perception)

Completed 86 enrolled University of Alabama at Birmingham American Society of Regional Anesthesia · collab

RandomizedParallel-groupOpen-label

Summary

The investigators propose to evaluate the potential effect of sedation on pain perception in two ways, by asking for a participant's pain rating(subjective) and by evaluating a subject's brain activation using fMRI(objective).

Timeline

Start: 2008-11
Primary completion: 2012-01
Completion: 2012-01

Publications

Results Frolich MA, Zhang K, Ness TJ. Effect of sedation on pain perception. Anesthesiology. 2013 Mar;118(3):611-21. doi: 10.1097/ALN.0b013e318281592d.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	—	Intravenous
Comparator	Midazolam	Small molecule	—	Intravenous
Comparator	Propofol	Small molecule	—	Intravenous

Indications

No indication recorded.