drugset / Trial / NCT00854139

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

NCT00854139

Phase 1 Completed 10 enrolled Massachusetts General Hospital
NaSingle-groupOpen-labelTreatment

Summary

The primary objective is to cure multiple myeloma with less toxic allogeneic bone marrow transplantation while inducing renal allograft tolerance through mixed chimerism in patients with end stage renal failure and multiple myeloma

Timeline

Start
2001-08
Primary completion
2014-07
Completion
2014-07

Drugs

EvaluationDrugModalityDoseRoute
Background ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) Protein / enzyme biologic 20 mg/kg Intravenous
Background Cyclophosphamide Other / unclassified 60 mg/kg Intravenous
Background Cyclosporine Peptide 3 mg/kg Intravenous