drugset / Trial / NCT00854178
Toxicogenomic and Immunocytotoxic Effects of Propofol and Isoflurane Anesthetics in Patients Undergoing Elective Surgery
Phase 4
Completed
26 enrolled
UPECLIN HC FM Botucatu Unesp
Fundação de Amparo à Pesquisa do Estado de São Paulo · collab
RandomizedParallel-groupDouble-blindSupportive care
Summary
The purpose of this study is to evaluate if the anesthetics propofol and isoflurane can damage DNA, induce apoptosis, change expression of genes related to apoptosis and DNA repair and change cytokines profile in patients submitted to elective surgery.
Timeline
- Start
- 2008-03
- Primary completion
- 2009-12
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isoflurane | Other / unclassified | 1 unknown | — |
| Subject | Propofol | Small molecule | 4 ug/ml | — |