drugset / Trial / NCT00856960
The Effect of Hypertension Medications on Renal Blood Flow Measurements in Healthy Males (MK-0000-127)
RandomizedCrossoverDouble-blindTreatment
Summary
This study will evaluate the effect of Aliskiren and Losartan on renal blood flow using PAH clearance, PC MRA and ASL MRI methodologies.
Timeline
- Start
- 2010-01
- Primary completion
- 2010-03
- Completion
- 2010-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aliskiren | Small molecule | 150 mg | — |
| Comparator | Aliskiren | Small molecule | 600 mg | — |
| Comparator | Losartan | Other / unclassified | 100 mg | — |