drugset / Trial / NCT00859352
AZD1981 Midazolam CYP4503A Induction Study
RandomizedParallel-groupOpen-labelBasic science
Summary
The primary objective of the study is to investigate if the exposure of midazolam is clinically significantly changed by 14 days of exposure to AZD1981 through possible enzyme induction of CYP3A.
Timeline
- Start
- 2009-03
- Primary completion
- —
- Completion
- 2009-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AZD1981 | Small molecule | 100 mg | Oral |
| Subject | AZD1981 | Small molecule | 500 mg | Oral |
| Subject | Midazolam | Small molecule | 7.5 mg | Oral |
Indications
No indication recorded.