Drugs / AZD1981
Trials 16
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 110 trials | ||||||
| Phase 1 | NCT01311635 | Apr → May 2011 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01254461 | Feb → Apr 2011 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01265641 | Jan → Apr 2011 | asthma | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01199341 | Oct → Dec 2010 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01196689 | Oct 2010 → Feb 2011 | asthma | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01110525 | May → Oct 2010 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01058447 | Feb → Mar 2010 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00918398 | Jun → Jul 2009 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00859352 | Mar → Apr 2009 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00698282 | Aug → Oct 2008 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 26 trials · 2 missed | ||||||
| Phase 2 | NCT02874144 | Jun 2016 → Jan 2020 | nasal cavity polyp | Northwestern University | Completed | No outcome recorded |
| Phase 2 | NCT02031679 | Jan 2014 → Jan 2016 | chronic idiopathic urticaria | Johns Hopkins University | Completed | No outcome recorded |
| Phase 2 | NCT01197794 | Oct 2010 → Feb 2012 | asthma | AstraZeneca | Completed | Missed primary |
| Phase 2 | NCT00766415 | Nov 2008 → Jun 2009 | chronic obstructive pulmonary disease | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00758589 | Sep 2008 → Jul 2009 | asthma | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00690482 | May → Dec 2008 | chronic obstructive pulmonary disease | AstraZeneca | Completed | Missed primary |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 18 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | AZD1981 | “AZD1981 is a selective antagonist of chemoattractant receptor-homologous molecule expressed on T helper type 2 and other type 2 cells, including innate lymphoid cells type 2,...” PMID 35524339 ↗ May 2022 |
| Action | Inhibit | “a potent, specific antagonist of the CRTh2 receptor” PMID 29765200 ↗ May 20181“G protein-coupled receptor 44 antagonist” CHEMBL1914489 ↗ |
| Modality | Small molecule | — CHEMBL1914489 ↗ |
| Route | Oral | “AZD1981 Oral tablet, twice daily” NCT00690482 ↗ |
| Target | PTGDR2 | “G protein-coupled receptor 44 antagonist” CHEMBL1914489 ↗ |