drugset / Trial / NCT00860925
PeriOperative ISchemic Evaluation-2 Pilot
Phase 4
Completed
90 enrolled
McMaster University
Canadian Network and Centre for Trials Internationally · collabThe Physicians' Services Incorporated Foundation · collab
RandomizedFactorialQuadruple-blindPrevention
Summary
Major non-cardiac surgeries are common and major heart problems during or after such surgeries represent a large population health problem. Few treatments to prevent heart problems around the time of surgery have been tested. There is encouraging data suggesting that low-doses of Acetyl-Salicylic Acid (ASA) and Clonidine, which are two medications, given individually for a short period before and after major surgeries may prevent major heart problems.
Timeline
- Start
- 2009-05
- Primary completion
- 2009-12
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetyl-Salicylic Acid | Unknown | 81 mg | Oral |
| Subject | Clonidine | Other / unclassified | 0.2 mg | Oral |