drugset / Trial / NCT00861523
Does Thiamine Help Vomiting and Nausea in Pregnancy?
RandomizedCrossoverOpen-labelTreatment
Summary
There are different treatments for nausea and vomiting in pregnancy. According to the ACOG recommendations, promethazine is the first line of parenteral treatment after oral treatment had failed. Thiamine is given to prevent wernicke encephalopathy. This research try to find out whether thiamine helps the vomiting and nausea as well, by comparing the response to thiamine and promethazine in women who suffer from nausea and vomiting in pregnancy.
Timeline
- Start
- 2009-02
- Primary completion
- 2012-01
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Promethazine | Small molecule | 25 mg | Intravenous |
| Comparator | Thiamine | Other / unclassified | 100 mg | Intravenous |