A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease

Summary

This study is intended to determine the safety and tolerance of regadenoson in subjects with asthma or chronic obstructive pulmonary disease.

Timeline

Start

2009-04

Primary completion

2009-10

Completion

2009-10

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Placebo - Asthma vs Regadenoson - Asthma; p = 0.1451; Cochran-Mantel-Haenszel NCT00862641 ↗

registry analysis (superiority or other test); Placebo - COPD vs Regadenoson - COPD; p = 0.5790; Cochran-Mantel-Haenszel NCT00862641 ↗

Publications

• Results Prenner BM, Bukofzer S, Behm S, Feaheny K, McNutt BE. A randomized, double-blind, placebo-controlled study assessing the safety and tolerability of regadenoson in subjects with asthma or chronic obstructive pulmonary disease. J Nucl Cardiol. 2012 Aug;19(4):681-92. doi: 10.1007/s12350-012-9547-4. Epub 2012 Apr 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Regadenoson	Diagnostic / imaging agent	0.4 mg	Intravenous

Indications