drugset / Trial / NCT00867035

Bad Breath Response to Tongue Scraper and Rinses

NCT00867035

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Medical center personnel were screened organoleptically for bad breath by 2 investigators using Rosenberg scale 0-5, and measurement of breath sample in portable gas chromatograph. With a threshold score of 2 or more, or 75parts per billion(ppb) hydrogen sulfide(H2S), subjects invited to enter clinical trial of the mechanical effect of daily tongue scraping with the adjunctive use of 0.12% chlorhexidine gluconate mouthwash or 0.1% stabilized chlorine dioxide mouthwash. Subjects randomly assigned in double-blind trial for one week. The null hypothesis is there will be no difference between the two rinses as adjuncts to tongue scraping.

Timeline

Start
2008-03
Primary completion
2009-03
Completion
2009-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine gluconate Other / unclassified 0.12 %
Comparator Chlorhexidine gluconate Other / unclassified 20 ml
Subject chlorine dioxide Unknown 0.1 %
Subject chlorine dioxide Unknown 20 ml

Indications

No indication recorded.