drugset / Trial / NCT00867035
Bad Breath Response to Tongue Scraper and Rinses
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Medical center personnel were screened organoleptically for bad breath by 2 investigators using Rosenberg scale 0-5, and measurement of breath sample in portable gas chromatograph. With a threshold score of 2 or more, or 75parts per billion(ppb) hydrogen sulfide(H2S), subjects invited to enter clinical trial of the mechanical effect of daily tongue scraping with the adjunctive use of 0.12% chlorhexidine gluconate mouthwash or 0.1% stabilized chlorine dioxide mouthwash. Subjects randomly assigned in double-blind trial for one week. The null hypothesis is there will be no difference between the two rinses as adjuncts to tongue scraping.
Timeline
- Start
- 2008-03
- Primary completion
- 2009-03
- Completion
- 2009-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine gluconate | Other / unclassified | 0.12 % | — |
| Comparator | Chlorhexidine gluconate | Other / unclassified | 20 ml | — |
| Subject | chlorine dioxide | Unknown | 0.1 % | — |
| Subject | chlorine dioxide | Unknown | 20 ml | — |
Indications
No indication recorded.