Enhancing Rehabilitation After Stroke

Summary

This is a 12-week, randomized, placebo controlled study to determine if donepezil (Aricept) treatment during rehabilitation after stroke improves functional recovery.

Timeline

Start

2009-03

Primary completion

2013-08

Completion

2013-11

Publications

• Background Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, Zheng ZJ, Flegal K, O'Donnell C, Kittner S, Lloyd JD, Goff DC, Hong Y, (2006): Heart Disease and Stroke Statistics-2006 Update, American Heart Association: February 14, 2006. http://circ.ahajournals.org/cgi/reprint/CIRCULATIONAHA.105.171600v1
• Background Whyte EM, Lenze EJ, Butters M, Skidmore E, Koenig K, Dew MA, Penrod L, Mulsant BH, Pollock BG, Cabacungan L, Reynolds CF 3rd, Munin MC. An open-label pilot study of acetylcholinesterase inhibitors to promote functional recovery in elderly cognitively impaired stroke patients. Cerebrovasc Dis. 2008;26(3):317-21. doi: 10.1159/000149580. Epub 2008 Jul 31.

Drugs

Indications