drugset / Trial / NCT00872521
A Study of Efficacy of Treatment With Bortezomib (in Combination With Doxorubicin and Dexamethasone) in Previously Untreated Patients With Multiple Myeloma
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine efficacy of treatment with bortezomib (in combination with doxorubicin and dexamethasone) in previously untreated patients with Multiple Myeloma.
Timeline
- Start
- 2009-01
- Primary completion
- 2011-03
- Completion
- 2011-11
Outcome
Missed primary endpoint
registry analysis (superiority or other test); 1q21 Not Amplified vs 1q21 Amplified; p = 0.09; Chi-squared NCT00872521 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bortezomib | Small molecule | 1.3 mg/m2 | Intravenous |
| Subject | Dexamethasone | Small molecule | 20 mg | Oral |
| Subject | Doxorubicin | Other / unclassified | 20 mg/m2 | Intravenous |