drugset / Trial / NCT00872651

Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension

NCT00872651

Phase 3 Completed 242 enrolled Alcon Research
RandomizedParallel-groupSingle-blindTreatment

Summary

Eligible patients will be randomized in a 1.1 ratio to receive Travoprost 0.004%/timolol 0.5% once daily or Latanoprost 0.005%/Timolol 0.5% once a day for 8 Weeks. The study treatments will be compared for mean diurnal intraocular pressure (IOP) change from baseline at Week 8. Safety parameters measured at 4 study visits: ocular signs, visual acuity, dilated fundus, cardiovascular parameters (blood pressure and pulse), and adverse events.

Timeline

Start
2010-01
Primary completion
2011-11
Completion
2011-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Latanoprost Small molecule 0.005 %
Comparator Timolol Other / unclassified 0.5 %
Subject Travoprost Other / unclassified 0.004 %