Comparison of Instillation and Packing in Mydriasis for Premature Infants

Summary

The purpose of this study is to compare the mydriatic effect of 2.5% phenylephrine and 1% tropicamide by conventional instillation and lower conjunctival fornix packing in premature infants.

Timeline

Start

2009-03

Primary completion

2009-05

Completion

2009-06

Outcome

Met primary endpoint

paper This difference was statistically significant (P < 0.05). PMID 22368443 ↗

paper The dilated pupil diameter after receiving the lower conjunctival fornix packing was larger than conventional instillation with a statistically significant difference. PMID 22368443 ↗

Publications

• Results Thanathanee O, Ratanapakorn T, Morley MG, Yospaiboon Y. Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial. Clin Ophthalmol. 2012;6:253-6. doi: 10.2147/OPTH.S28714. Epub 2012 Feb 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Phenylephrine	Small molecule	2.5 %	Topical
Subject	tropicamide	Small molecule	1 %	Topical

Indications

No indication recorded.