drugset / Trial / NCT00877799
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to determine the effectiveness and safety of single intravenous doses of the kappa opioid agonist CR845 in relieving pain in patients following laparoscopic-assisted hysterectomy surgery. The study protocol was divided into two parts with subjects either dosed with study drug the day following surgery (Cohort 1), or immediately after surgery (Cohort 2).
Timeline
- Start
- 2009-03
- Primary completion
- 2009-12
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Difelikefalin | Protein / enzyme biologic | 0.008 mg/kg | Intravenous |
| Subject | Difelikefalin | Protein / enzyme biologic | 0.024 mg/kg | Intravenous |
| Subject | Difelikefalin | Protein / enzyme biologic | 0.04 mg/kg | Intravenous |
Indications
No indication recorded.