drugset
drugset / Trial / NCT00884832

A Placebo-Controlled Study of Clonidine for Fecal Incontinence.

NCT00884832 ↗

Phase 2 Completed 44 enrolled Mayo Clinic National Center for Research Resources (NCRR) · collabNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab
RandomizedParallel-groupTriple-blindTreatment

Summary

Fecal incontinence is the involuntary leakage of stool from the anus. Doctors at Mayo Clinic are doing a research study to assess the effects of a medication, clonidine, on fecal incontinence and rectal functions in women. Clonidine has been approved by the Food and Drug Administration (FDA) for treating high blood pressure, but not for treating incontinence and rectal functions. The hypothesis of this study is clonidine will improve fecal incontinence, increase rectal capacity and reduce rectal sensation to a greater extent than placebo in women.

Timeline

Start
2008-10
Primary completion
2012-08
Completion
2012-08

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Clonidine Other / unclassified 0.1 mg Oral

Indications

No indication recorded.