drugset / Trial / NCT00889499
Modulation of Central Hypersensitivity in Chronic Musculoskeletal Pain by Intravenous Tropisetron
RandomizedCrossoverDouble-blindTreatment
Summary
Chronic pain is associated with hypersensitivity of the central nervous system. The drug under investigation (tropisetron) has been shown in animal studies to attenuate central hypersensitivity. It has therefore the potential to be effective in chronic pain. We compare two doses of tropisetron with placebo in patients with chronic pain. We measure pain intensity and parameters that assess central hypersensitivity.
Timeline
- Start
- 2009-03
- Primary completion
- 2010-04
- Completion
- 2010-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tropisetron | Small molecule | 2 mg | Intravenous |
| Comparator | Tropisetron | Small molecule | 5 mg | Intravenous |
Indications
No indication recorded.